Bitteraneo Mediterranean Mastiha Bitters. Bitteraneo Mediterranean Mastiha Bitters is produced exclusively from natural Mediterranean ingredients 100% natural bitter extracts of excellent quality and high concentration, for a great performance and intense aroma and flavour. Every drop is a precious tear of the unique mastic of Chios island (“mastiha”), with a discreet aftertaste of fresh mastic water and the mastic tree’s wood. Artemisia balances the bitterness and just a bit of Greek honey gives a golden touch.